Systemic Review and Role of Zebrafish as a Pharmacological Model
Keywords:
Zebrafish, Toxicity screening, Alzheimer's disease model, Parkinson's disease model, Diabetes mellitus model, Cancer researchAbstract
Zebrafish (Danio rerio) are transforming drug discovery and safety assessment. Their genetic similarity and transparent embryos enable real-time visualization of drug effects. This has led to breakthroughs in neuropharmacology, cardiology, and oncology, paving the way for personalized medicine. Zebrafish also provide a cost-effective and ethical alternative for toxicology testing. Their sensitivity to toxins and human-like development aid in identifying potential hazards. This has informed risk assessment and the development of safer, more efficacious therapeutics. Overall, this systematic review demonstrates the significant role of zebrafish as a pharmacological model and underscores its importance in advancing drug discovery and development. Future research utilizing zebrafish is expected to further enhance our understanding of pharmacology and lead to the development of new and effective therapeutics for various diseases.
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