A Review on Sustained Release Matrix Tablet
A Recent Approach for Oral Drug Delivery System
Keywords:
sustained release, drug delivery, matrix system, tablet, polymerAbstract
Sustained release formulations are advanced drug delivery systems designed to release active pharmaceutical ingredients (APIs) over an extended period, maintaining therap-eutic levels and reducing dosing frequency. These formulations enhance patient compliance, reduce side effects, and improve bioavailability. This review explores recent advancements in sustained release technologies, including Matrix systems, Reservoir systems, Microencapsulation, Nanoparticles, and Liposomes. Factors influencing drug release, such as polymer degradation, diffusion, and erosion, are discussed. Applications in various therapeutic areas, including chronic pain management, antihypertensives, and HIV treatment, are highlighted. Challenges and future directions in sustained release formulation development are also addressed.
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