Anti-Inflammatory and Antioxidant Properties of Pavonia zeylonica Root Extracts

Abstract

Various analysis works are perusing stress-related disorders caused by the buildup of free radicals in the body around the world to explore natural antioxidants derived from plants. The objectives of this work were to assess in vitro antioxidant activity and anti-inflammatory activity and to identify phytochemical elements of Pavonia zeylonica in ethanol, petroleum ether, and aqueous root extracts. We evaluated the antioxidant potential and phytochemical contents of petroleum ether, ethanol, and aqueous root extracts of Pavonia zeylonica using DPPH, ABTS radical cation scavenging activity, ferric reducing antioxidant power assay, superoxide radical scavenging activity, and nitric oxide scavenging activity. The extracts flavonoid, tannin, and phenolic contents were also measured using established phytochemical reaction methods. Alkaloids, flavonoids, steroids, anthraquinones, proteins, phenols, saponins, and carbohydrates were discovered by phytochemical analysis. The total phenolic, flavonoid, and tannin contents of the ethanol root extract were quantified as 69.32, 28.39, and 58.45 mg of rutin and gallic acid equivalent/g of extract, respectively. Anti-inflammatory various concentration extracts of the root evaluated using the method of induced hemolysis and heat-induced hemolysis. The antioxidant activity of various concentrations and extracts of the root were evaluated using five test methods. Ethanol extract of the root responded for good antioxidant activity in all experimental methodologies. The findings of the current study suggested that the ethanol root of Pavonia zeylonica is a potential source of natural antioxidants and inflammation disorders.