Evaluation of Anti-Oxidant and Anthelmintic Activity of Hibiscus cannabinus Seed Extract

Authors

  • A. M. Krupanidhi Department of Pharmacology, Bapuji Pharmacy College, Davangere-577004, India
  • N. S. Ujwala Department of Pharmacology, Bapuji Pharmacy College, Davangere-577004, India
  • Shanthana Gowda G. S. Department of Pharmacology, Bapuji Pharmacy College, Davangere-577004, India
  • Pooja T. Department of Pharmacology, Bapuji Pharmacy College, Davangere-577004, India
  • G. Sanjay Department of Pharmacology, Bapuji Pharmacy College, Davangere-577004, India
  • Sharath Kanti K. T. Department of Pharmacology, Bapuji Pharmacy College, Davangere-577004, India

Keywords:

Hibiscus cannabinus, Antioxidant, Anthelmintic, Seed extract

Abstract

This study explores the Antioxidant and Anthelmintic activities of Hibiscus cannabinus seed extract by Maceration process, aiming to evaluate its therapeutic potential. The Antioxidant activity was assessed using DPPH, revealing significant free radical scavenging properties with IC50 values (97.62µg/ml) comparable to standard Antioxidants. The presence of bioactive compounds, such as Alkaloids Flavonoids, Taninns, Steroids, Terpenoids, Phenolic compounds, likely contributes to this activity. The Anthelmintic efficacy was determined using paralysis and mortality of helminths, demonstrating dose-dependent activity. The findings suggest that Hibiscus cannabinus seed extract exhibits promising natural Antioxidant and Anthelmintic properties, potentially beneficial for Pharmaceutical and Agricultural applications. Further studies are warranted to isolate active compounds and elucidate mechanisms of action. This research supports the sustainable use of natural resources for developing safe, cost-effective therapeutic agents.

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Published

11-12-2024

How to Cite

Krupanidhi, A. M., Ujwala, N. S., Shanthana Gowda, G. S., Pooja, T., Sanjay, G., & Sharath Kanti, K. T. (2024). Evaluation of Anti-Oxidant and Anthelmintic Activity of Hibiscus cannabinus Seed Extract. Inventum Biologicum: An International Journal of Biological Research, 4(4), 175–182. Retrieved from https://journals.worldbiologica.com/ib/article/view/146

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Research article