Chemistry and Anti-Cancer Potential of Benzotriazole (BT) Subordinates

Gargi Pal; Subhajit Makar; Pratap Chandra Pradhan; Dhirendra Nath Gan; Hemanta Kumar Khatua; Saroj Kumar Sethi; Ranjan Krushna Kumar Patra

المؤلفون

Gargi Pal Assistant Professor, Department of Pharmaceutics, Institute of Pharmaceutical Sciences, Jaleswar, Balasore, Odisha, India-756032
Subhajit Makar Assistant Professor, Department of Pharm. Chem., Institute of Pharmaceutical Sciences, Jaleswar, Balasore, Odisha, India-756032
Pratap Chandra Pradhan Director, Mothers’ Group of Institution, Institute of Pharmaceutical Sciences, Jaleswar, Balasore, Odisha, India-756032
Dhirendra Nath Gan Assistant Professor, Department of Pharmaceutics, Institute of Pharmaceutical Sciences, Jaleswar, Balasore, Odisha, India-756032
Hemanta Kumar Khatua Assistant Professor, Department of Pharm. Chem., Institute of Pharmaceutical Sciences, Jaleswar, Balasore, Odisha, India-756032
Saroj Kumar Sethi Assistant Professor, Department of Pharmaceutics, Institute of Pharmaceutical Sciences, Jaleswar, Balasore, Odisha, India-756032
Ranjan Krushna Kumar Patra Assistant Professor, Department of Pharmaceutics, Institute of Pharmaceutical Sciences, Jaleswar, Balasore, Odisha, India-756032

الكلمات المفتاحية:

Benzotriazole، Anti-Cancer، Synthetic، Chemistry، Drug development

الملخص

Benzotriazole is a bicyclic heterocyclic system consisting of three nitrogen atoms and fused benzene ring, shows wide range of biological and pharmacological activities. Benzotriazole can be synthesized using benzene-1,2-diamine, and carboxylic acid. Benzotriazole possess wide spectrum of biological activities like including anticancer, antibacterial, antifungal, antiviral, anti-inflammatory, antihypertensive, analgesic properties. The present reviews attempted to gather the various developments in chemistry, synthetic advancement, and anticancer activities of benzotriazole derivatives. This review is focused on defining the place of benzotriazole derivatives in biomedical research, highlighting their mode of action and Structure Activity Relationship (SAR) studies for anticancer drug development.

التنزيلات

بيانات التنزيل غير متوفرة بعد.

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